PLEKHO1 ELISA Kit for Bovine(Bos taurus) | EIAab.comPLEKHO1 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > PLEKHO1(Gene name) > Bovine

PLEKHO1 (Gene name),

Pleckstrin homology domain-containing family O member 1 (Protein name ), PKHO1_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PLEKHO1;

Protein name:

Pleckstrin homology domain-containing family O member 1(PH domain-containing family O member 1);

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Heterodimer or homodimer. Interacts with CK2 and actin capping subunits (capping protein CP-alpha and CP-beta). CKIP1 and CK2 together inhibit the activity of actin capping protein at the barbed ends of actin filaments. Interacts with ATM, IFP35, JUN, JUND, NMI and PI3K. Interacts with AKT1, AKT2 and AKT3 (each isozyme of PKB), PtdIns(3,5)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P2.

Function:

Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

Subcellular Location:

Membrane Nucleus Cytoplasm

Protein Attributes:

Sequence length:

409

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

409:

HSQYRKSLM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

bta:788251

STRING:

9913.ENSBTAP00000006381

Pfam:

PF00169

UniGene:

Bt.20245

Uniprot:

A4IFK0

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ELISA Kit for Bovine PH domain-containing family O member 1

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ELISA Kit for Bovine PH domain-containing family O member 1

Cat.:

E15005h

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Packing:

96T

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ELISA Kit for Bovine PH domain-containing family O member 1

MSDS:

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ELISA Kit for Bovine PH domain-containing family O member 1

MSDS:

Please sign in first.

ELISA Kit for Bovine PH domain-containing family O member 1

MSDS:

Please sign in first.